About This Database
Comparasite, an integrated database of our original full-length cDNA sequence data, consists of seven sub-databases of apicomplexa protozoa, Plasmodium.falciparum(12,484 cDNA sequences), Plasmodium. yoelii (11,262 sequences), Plasmodium vivax (9,633 sequences), Plasmodium. berghei (1,518 sequences), Toxoplasma gondii (7,400 sequences), Cryptosporidium parvum (5,921 sequences) and a tapeworm, Echinococcus multilocularis (10,966 sequences).
Homologous gene groups are clustered and comparative analysis of any combination of these seven species is implemented, such as interspiceis comparisons as to cellular localization, motifs or transmembrane regions and so on. For submitted keywords and other search conditions, Comparasite retrieves orthologous gene groups containing a given protein motif/GO term etc in common or in a species-specific manner.
By enabling multi-faceted comparative analyses of genes of apicomplexa protozoa, monophyletic organisms that have evolved to diversify to parasitize various hosts by adopting complex life cycles, Comparasite should help elucidate the mechanism behind parasitism.
- Experimental Procedures